Why is aspirin combined with maalox

The results show that antacid affected the relative bioavailability of aspirin since the mean peak concentration Cmax of aspirin was significantly higher when antacid was given. However, the time to reach peak concentration Tmax and the area under the plasma concentration-time curve AUC showed no significant difference between the two treatments.

It was, therefore, not possible to conclude that the non-bioequivalence was caused by a difference in rate or amount of aspirin absorption, or both. However, the rate of total salicylate absorption was increased since the absorption rate constant Ka was higher when antacid was given. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Before taking aspirin, tell your doctor or pharmacist if you are allergic to it; or to other salicylates such as choline salicylate ; or to other pain relievers or fever reducers NSAIDs such as ibuprofen, naproxen ; or if you have any other allergies.

This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:. If you have any of the following health problems, consult your doctor or pharmacist before using this medication:. This medicine may cause stomach bleeding.

Daily use of alcohol and tobacco, especially when combined with this product, may increase your risk for this side effect. Limit alcoholic beverages, and stop smoking. Check with your doctor or pharmacist for more information. Children and teenagers less than 18 years old should not take aspirin if they have chickenpox, flu, or any undiagnosed illness or if they have recently received a vaccine. In these cases, taking aspirin increases the risk of Reye's syndrome, a rare but serious illness.

Tell your doctor promptly if you see changes in behavior with nausea and vomiting. This may be an early sign of Reye's syndrome. Aspirin is not recommended for use during pregnancy. Consult your doctor before using this medication if you are or think you may be pregnant. Tell your doctor right away if you become pregnant while taking this medication. Do not use this medication during the last 3 months of pregnancy because of possible harm to the unborn baby or problems during delivery.

Aspirin passes into breast milk and may harm the nursing infant. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Before using this product, consult your doctor if you have recently received certain live vaccines such as varicella vaccine, live flu vaccine. To prevent an overdose of aspirin, read the labels carefully before taking other pain relievers or cold products to make sure they do not contain aspirin. Ask your pharmacist about using these products safely. This medication may interfere with certain laboratory tests including certain urine sugar tests , possibly causing false test results.

Make sure laboratory personnel and all your doctors know you are taking this medication. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center. Consult your doctor for more details. There are many different aspirin products. Some have special coatings and some are long-acting.

Ask your doctor or pharmacist to recommend the best product for you. If your doctor directs you to take this drug on a regular schedule not just "as needed" and you miss a dose, take it as soon as you remember.

For occasional heartburn or acid reflux, antacids may help. They work by neutralizing the stomach acid that irritates the stomach and esophagus. Examples of antacids you'll find at your local supermarket or pharmacy include: Tums calcium carbonate Citrical calcium citrate Gaviscon alginic acid Alka-Seltzer sodium bicarbonate Drugs containing a combination of aluminum and magnesium, such as Mylanta , Maalox, and Gelusil Some of these brands — like Gelusil, Mylanta Extra Strength, and Maalox Advanced — may also contain simethicone to control gas.

Warnings, Precautions, and Drug Interactions Stop taking antacids and contact your doctor if you've been using antacids for 2 weeks with no improvement in your symptoms. Ask your doctor before taking antacids if you:.